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Psoriasis patients previously treated with PUVA and to a lesser extent, methotrexate or other immunosuppressive agents, UVB, coal tar, or radiation therapy, are at an increased risk of developing skin malignancies when taking Cyclosporine Capsules USP (Modified).
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Safety and effectiveness has not been established in dogs less than 6 months or 4 lbs.
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The risk increases with increasing doses of Cyclosporine.
The recognition that cyclosporine has immunosuppressive properties has led to its use in patients with severe ulcerative colitis, with variable results.
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As atopic dermatitis in dogs cannot be cured its treatment revolves around management and treatments are often required over long periods of time.
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Of the eight patients receiving vehicle, one had moderate improvement with respect to erythema and erosion, five remained essentially unchanged, and two had ulcerative flare-ups requiring them to withdraw from the double-blind phase after receiving vehicle for six weeks.
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Cyclosporine has been shown to be efficacious in the treatment of many inflammatory dermatoses when given systemically.
Do not use this medication without telling your doctor if you are breast-feeding a baby.
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