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Because diltiazem is also used as a hypertensive agent, the largest risk associated with suprapotent topical 2% diltiazem might be dizziness or postural hypotension.

Five of the 12 pharmacies compounded 2% diltiazem as a cream, using lipoderm, but 6 of the 12 pharmacies compounded 2% diltiazem as an ointment, using petrolatum.

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When used concomitantly, anesthetics and calcium channel blockers should be titrated carefully.

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Ointments were applied to the perianal region three times daily for seven days.

Chronicity of fissures relates to duration of greater than 6 weeks, associated pathology may include a sentinel pile.

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Just had my second Sphincterotomy Surgery done four days ago, the first one was done 3 years ago, I have IBS ( or so the doctors say ), So over usage of the area caused fissures which were very painful, I feel like I was hit with a baseball bat several times plus I also have the feeling of an ice-pik inside of my anus, Don't know if this is a condition which will continue seing that my stomach alwas wants to push my food down and my bottom's in pain and sometimes can not be in synch.

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This is also important after surgery because straining and passage of hard stools increase pain and bleeding, and delay healing.

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